SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells

WNT/β-catenin signaling controls gene expression across biological contexts from development and stem cell homeostasis to diseases including cancer. How β-catenin is recruited to distinct enhancers to activate context-specific transcription is unclear, given that most WNT/ß-catenin-responsive transc...

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Detalles Bibliográficos
Autores principales: Mukherjee, Shreyasi, Luedeke, David M., McCoy, Leslie, Iwafuchi, Makiko, Zorn, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123531/
https://www.ncbi.nlm.nih.gov/pubmed/36001974
http://dx.doi.org/10.1016/j.celrep.2022.111247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123531/
https://www.ncbi.nlm.nih.gov/pubmed/36001974
http://dx.doi.org/10.1016/j.celrep.2022.111247

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