Cargando…

SOX transcription factors direct TCF-independent WNT/β-catenin responsive transcription to govern cell fate in human pluripotent stem cells

WNT/β-catenin signaling controls gene expression across biological contexts from development and stem cell homeostasis to diseases including cancer. How β-catenin is recruited to distinct enhancers to activate context-specific transcription is unclear, given that most WNT/ß-catenin-responsive transc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mukherjee, Shreyasi, Luedeke, David M., McCoy, Leslie, Iwafuchi, Makiko, Zorn, Aaron M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123531/ https://www.ncbi.nlm.nih.gov/pubmed/36001974 http://dx.doi.org/10.1016/j.celrep.2022.111247

Ejemplares similares

SOX9 and TCF transcription factors associate to mediate Wnt/β-catenin target gene activation in colorectal cancer
por: Ramakrishnan, Aravinda-Bharathi, et al.
Publicado: (2022)

Sox17 and β-catenin co-occupy Wnt-responsive enhancers to govern the endoderm gene regulatory network
por: Mukherjee, Shreyasi, et al.
Publicado: (2020)

Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
por: Lien, Wen-Hui, et al.
Publicado: (2014)

Pioneer transcription factors in cell reprogramming
por: Iwafuchi-Doi, Makiko, et al.
Publicado: (2014)

VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
por: Zhang, Haifeng, et al.
Publicado: (2021)

Repression of Wnt/β-catenin signaling by SOX9 and Mastermind-like transcriptional coactivator 2
por: Sinha, Abhishek, et al.
Publicado: (2021)

The mechanistic basis for chromatin regulation by pioneer transcription factors
por: Iwafuchi‐Doi, Makiko
Publicado: (2018)

Dazap2 modulates transcription driven by the Wnt effector TCF-4
por: Lukas, Jan, et al.
Publicado: (2009)

Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity
por: He, Xiaoli, et al.
Publicado: (2017)

A switch in transcription and cell fate governs the onset of an epigenetically-deregulated tumor in Drosophila
por: Torres, Joana, et al.
Publicado: (2018)

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency
por: Athanasouli, Paraskevi, et al.
Publicado: (2023)

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets
por: Weise, Andreas, et al.
Publicado: (2010)

Transcriptional network governing extraembryonic endoderm cell fate choice
por: Pham, Paula Duyen, et al.
Publicado: (2023)

Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5
por: Choi, Eun-Bee, et al.
Publicado: (2023)

Krueppel-like factor 15 regulates Wnt/β-catenin transcription and controls cardiac progenitor cell fate in the postnatal heart
por: Noack, Claudia, et al.
Publicado: (2012)

A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators
por: Freeman, Jamie, et al.
Publicado: (2015)

Targets of Wnt/ß-Catenin Transcription in Penile Carcinoma
por: Arya, Manit, et al.
Publicado: (2015)

Deciphering the Transcriptional Landscape of Human Pluripotent Stem Cell-Derived GnRH Neurons: The Role of Wnt Signaling in Patterning the Neural Fate
por: Wang, Yafei, et al.
Publicado: (2022)

SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity
por: Zuo, Chunlin, et al.
Publicado: (2018)

Tcf-3 expression and β -catenin mediated transcriptional activation in aggressive fibromatosis (desmoid tumour)
por: Tejpar, S, et al.
Publicado: (2001)

The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated Transcription
por: Abdel-Rahman, Wael M., et al.
Publicado: (2016)

Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions
por: Strebinger, Daniel, et al.
Publicado: (2019)

SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of β-Catenin in Lung Cancer
por: Han, Fei, et al.
Publicado: (2018)

Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression
por: Wallmen, Britta, et al.
Publicado: (2012)

Mammalian Nemo-like kinase enhances β-catenin-TCF transcription activity in human osteosarcoma and neuroblastoma cells
por: Yasuda, Jun, et al.
Publicado: (2007)

Structure-Function Analysis of the C-clamp of TCF/Pangolin in Wnt/ß-catenin Signaling
por: Ravindranath, Aditi, et al.
Publicado: (2014)

Evolution of non-coding regulatory sequences involved in the developmental process: Reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes
por: Kamachi, Yusuke, et al.
Publicado: (2009)

PARsylated transcription factor EB (TFEB) regulates the expression of a subset of Wnt target genes by forming a complex with β-catenin-TCF/LEF1
por: Kim, Soyoung, et al.
Publicado: (2021)

FOX transcription factors are common regulators of Wnt/β-catenin–dependent gene transcription
por: Moparthi, Lavanya, et al.
Publicado: (2023)

Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells
por: Buongiorno, Pinella, et al.
Publicado: (2008)

Gamma-Secretase-Dependent and -Independent Effects of Presenilin1 on β-Catenin·Tcf-4 Transcriptional Activity
por: Raurell, Imma, et al.
Publicado: (2008)

MENA Is a Transcriptional Target of the Wnt/Beta-Catenin Pathway
por: Najafov, Ayaz, et al.
Publicado: (2012)

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer
por: Bian, Jia, et al.
Publicado: (2020)

Wnt/β-Catenin-Dependent Transcription in Autism Spectrum Disorders
por: Caracci, Mario O., et al.
Publicado: (2021)

Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells
por: Kim, Ji Young, et al.
Publicado: (2018)

The Transcription Factor TCF1 in T Cell Differentiation and Aging
por: Kim, Chulwoo, et al.
Publicado: (2020)

Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10
por: Li, Nan, et al.
Publicado: (2015)

Genetic Variants of Wnt Transcription Factor TCF-4 (TCF7L2) Putative Promoter Region Are Associated with Small Intestinal Crohn's Disease
por: Koslowski, Maureen J., et al.
Publicado: (2009)

Tcf15 Primes Pluripotent Cells for Differentiation
por: Davies, Owen R., et al.
Publicado: (2013)

S100A4/TCF Complex Transcription Regulation Drives Epithelial-Mesenchymal Transition in Chronic Sinusitis Through Wnt/GSK-3β/β-Catenin Signaling
por: Gong, Ningyue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2rs83o7m9p5s7c4esvckqhhia3