The deubiquitinase OTUD4 inhibits the expression of antimicrobial peptides in Paneth cells to support intestinal inflammation and bacterial infection

Dysfunction of the intestinal epithelial barrier causes microbial invasion that would lead to inflammation in the gut. Antimicrobial peptides (AMPs) are essential components of the intestinal epithelial barrier, while the regulatory mechanisms of AMPs expression are not fully characterized. Here, we...

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Detalles Bibliográficos
Autores principales: Yu, Keying, Guo, Yu-Yao, Liuyu, Tianzi, Wang, Peng, Zhang, Zhi-Dong, Lin, Dandan, Zhong, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123543/
https://www.ncbi.nlm.nih.gov/pubmed/37193092
http://dx.doi.org/10.1016/j.cellin.2023.100100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123543/
https://www.ncbi.nlm.nih.gov/pubmed/37193092
http://dx.doi.org/10.1016/j.cellin.2023.100100

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