An Antibody Targeting Fibroblast Activation Protein Simultaneously Fused to Interleukin-2 and Tumor Necrosis Factor Selectively Localizes to Neoplastic Lesions

The delivery of specific cytokine payloads to a neoplastic environment employing antibodies able to selectively accumulate at the tumor site represents an attractive strategy to stimulate an immune response to cancer. Whilst conventional antibody–cytokine fusions based on a single payload have shown...

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Detalles Bibliográficos
Autores principales: Prodi, Eleonora, Comacchio, Claudia, Gilardoni, Ettore, Di Nitto, Cesare, Puca, Emanuele, Neri, Dario, De Luca, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123652/
https://www.ncbi.nlm.nih.gov/pubmed/37092450
http://dx.doi.org/10.3390/antib12020029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123652/
https://www.ncbi.nlm.nih.gov/pubmed/37092450
http://dx.doi.org/10.3390/antib12020029

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