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Single-cell multiome sequencing clarifies enteric glial diversity and identifies an intraganglionic population poised for neurogenesis

The enteric nervous system (ENS) consists of glial cells (EGCs) and neurons derived from neural crest precursors. EGCs retain capacity for large-scale neurogenesis in culture, and in vivo lineage tracing has identified neurons derived from glial cells in response to inflammation. We thus hypothesize...

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Detalles Bibliográficos
Autores principales: Guyer, Richard A., Stavely, Rhian, Robertson, Keiramarie, Bhave, Sukhada, Mueller, Jessica L., Picard, Nicole M., Hotta, Ryo, Kaltschmidt, Julia A., Goldstein, Allan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123761/
https://www.ncbi.nlm.nih.gov/pubmed/36857184
http://dx.doi.org/10.1016/j.celrep.2023.112194