Melatonin attenuated chronic visceral pain by reducing Na(v)1.8 expression and nociceptive neuronal sensitization

BACKGROUND: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, and its specific pathogenesis is still unclear. We have previously reported that TTX-resistant (TTX-R) sodium channels in colon-specific dorsal root ganglion (DRG) neurons were sensitized in a rat model of v...

Descripción completa

Detalles Bibliográficos
Autores principales: Lv, Meng-Dan, Wei, Ying-Xue, Chen, Jian-Peng, Cao, Ming-Yao, Wang, Qian-Liang, Hu, Shufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123881/
https://www.ncbi.nlm.nih.gov/pubmed/37002193
http://dx.doi.org/10.1177/17448069231170072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123881/
https://www.ncbi.nlm.nih.gov/pubmed/37002193
http://dx.doi.org/10.1177/17448069231170072

Ejemplares similares