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Melatonin attenuated chronic visceral pain by reducing Na(v)1.8 expression and nociceptive neuronal sensitization

BACKGROUND: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, and its specific pathogenesis is still unclear. We have previously reported that TTX-resistant (TTX-R) sodium channels in colon-specific dorsal root ganglion (DRG) neurons were sensitized in a rat model of v...

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Detalles Bibliográficos
Autores principales:	Lv, Meng-Dan, Wei, Ying-Xue, Chen, Jian-Peng, Cao, Ming-Yao, Wang, Qian-Liang, Hu, Shufen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123881/ https://www.ncbi.nlm.nih.gov/pubmed/37002193 http://dx.doi.org/10.1177/17448069231170072

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