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Loss of Stat3 in Osterix(+) cells impairs dental hard tissues development

BACKGROUND: Mutations in the signal transducers and activators of transcription 3 (STAT3) gene result in hyper-IgE syndrome(HIES), a rare immunodeficiency that causes abnormalities in immune system, bones and teeth. However, the role of Stat3 in development of dental hard tissues was yet to investig...

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Detalles Bibliográficos
Autores principales: Chan, Laiting, Lu, Jiarui, Feng, Xin, Lin, Lichieh, Yao, Yichen, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123978/
https://www.ncbi.nlm.nih.gov/pubmed/37088831
http://dx.doi.org/10.1186/s13578-023-01027-1