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A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA

BACKGROUND: Extensive studies have revealed the function and mechanism of lncRNAs in development and differentiation, but the majority have focused on those lncRNAs adjacent to protein-coding genes. In contrast, lncRNAs located in gene deserts are rarely explored. Here, we utilize multiple different...

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Detalles Bibliográficos
Autores principales: Lu, Pei, Yang, Jie, Li, Mao, Wen, Shanshan, Zhang, Tianzhe, Yan, Chenchao, Liu, Ran, Xiao, Yu, Wang, Xinghuan, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124006/
https://www.ncbi.nlm.nih.gov/pubmed/37095549
http://dx.doi.org/10.1186/s13059-023-02925-w