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Safe shortening of antibiotic treatment duration for complicated Staphylococcus aureus bacteraemia (SAFE trial): protocol for a randomised, controlled, open-label, non-inferiority trial comparing 4 and 6 weeks of antibiotic treatment

INTRODUCTION: A major knowledge gap in the treatment of complicated Staphylococcus aureus bacteraemia (SAB) is the optimal duration of antibiotic therapy. Safe shortening of antibiotic therapy has the potential to reduce adverse drug events, length of hospital stay and costs. The objective of the SA...

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Detalles Bibliográficos
Autores principales: Buis, DTP, van Werkhoven, CH, van Agtmael, MA, Bax, HI, Berrevoets, M, de Boer, MGJ, Bonten, MJM, Bosmans, JE, Branger, J, Douiyeb, S, Gelinck, LBS, Jong, E, Lammers, AJJ, Van der Meer, JTM, Oosterheert, JJ, Sieswerda, E, Soetekouw, R, Stalenhoef, JE, Van der Vaart, TW, Bij de Vaate, EA, Verkaik, NJ, Van Vonderen, MGA, De Vries, PJ, Prins, JM, Sigaloff, KCE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124302/
https://www.ncbi.nlm.nih.gov/pubmed/37085305
http://dx.doi.org/10.1136/bmjopen-2022-068295