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Evolution of the SARS-CoV-2 Mutational Spectrum

SARS-CoV-2 evolves rapidly in part because of its high mutation rate. Here, we examine whether this mutational process itself has changed during viral evolution. To do this, we quantify the relative rates of different types of single-nucleotide mutations at 4-fold degenerate sites in the viral genom...

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Detalles Bibliográficos
Autores principales: Bloom, Jesse D, Beichman, Annabel C, Neher, Richard A, Harris, Kelley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124870/
https://www.ncbi.nlm.nih.gov/pubmed/37039557
http://dx.doi.org/10.1093/molbev/msad085