Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3

Cardiac contraction is modulated by the phosphorylation state of myosin regulatory light chain 2 (MLC-2v). The level of MLC-2v phosphorylation is dependent on the opposing activities of MLC kinases and phosphatases. The predominant MLC phosphatase found in cardiac myocytes contains Myosin Phosphatas...

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Detalles Bibliográficos
Autores principales: Hu, Tingfei, Kalyanaraman, Hema, Pilz, Renate B., Casteel, Darren E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124902/
https://www.ncbi.nlm.nih.gov/pubmed/36889588
http://dx.doi.org/10.1016/j.jbc.2023.104584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124902/
https://www.ncbi.nlm.nih.gov/pubmed/36889588
http://dx.doi.org/10.1016/j.jbc.2023.104584

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