The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11

A successful HIV-1 cure strategy may require enhancing HIV-1 latency to silence HIV-1 transcription. Modulators of gene expression show promise as latency-promoting agents in vitro and in vivo. Here, we identify Su(var)3–9, enhancer-of-zeste, and trithorax (SET) and myeloid, Nervy, and DEAF-1 (MYND)...

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Detalles Bibliográficos
Autores principales: Boehm, Daniela, Lam, Victor, Schnolzer, Martina, Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124996/
https://www.ncbi.nlm.nih.gov/pubmed/36897778
http://dx.doi.org/10.1016/j.celrep.2023.112234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10124996/
https://www.ncbi.nlm.nih.gov/pubmed/36897778
http://dx.doi.org/10.1016/j.celrep.2023.112234

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