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IL11 (Interleukin-11) Causes Emphysematous Lung Disease in a Mouse Model of Marfan Syndrome

Marfan Syndrome (MFS) is an inherited connective tissue disorder caused by mutations in the FBN1 (fibrillin-1) gene. Lung abnormalities are common in MFS, but their pathogenesis is poorly understood. IL11 (interleukin-11) causes aortic disease in a mouse model of MFS and was studied here in the lung...

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Detalles Bibliográficos
Autores principales: Ng, Benjamin, Xie, Chen, Su, Liping, Kuthubudeen, Fathima F., Kwek, Xiu-Yi, Yeong, Daryl, Pua, Chee Jian, Cook, Stuart A., Lim, Wei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125130/
https://www.ncbi.nlm.nih.gov/pubmed/36924234
http://dx.doi.org/10.1161/ATVBAHA.122.318802