Cargando…
IL11 (Interleukin-11) Causes Emphysematous Lung Disease in a Mouse Model of Marfan Syndrome
Marfan Syndrome (MFS) is an inherited connective tissue disorder caused by mutations in the FBN1 (fibrillin-1) gene. Lung abnormalities are common in MFS, but their pathogenesis is poorly understood. IL11 (interleukin-11) causes aortic disease in a mouse model of MFS and was studied here in the lung...
Autores principales: | Ng, Benjamin, Xie, Chen, Su, Liping, Kuthubudeen, Fathima F., Kwek, Xiu-Yi, Yeong, Daryl, Pua, Chee Jian, Cook, Stuart A., Lim, Wei-Wen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125130/ https://www.ncbi.nlm.nih.gov/pubmed/36924234 http://dx.doi.org/10.1161/ATVBAHA.122.318802 |
Ejemplares similares
-
The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling
por: Dong, Jinrui, et al.
Publicado: (2021) -
IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis
por: Ng, Benjamin, et al.
Publicado: (2022) -
Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models
por: Lim, Wei-Wen, et al.
Publicado: (2020) -
Transgenic interleukin 11 expression causes cross-tissue fibro-inflammation and an inflammatory bowel phenotype in mice
por: Lim, Wei-Wen, et al.
Publicado: (2020) -
Interleukin 11 (IL-11): Role(s) in Breast Cancer Bone Metastases
por: Maroni, Paola, et al.
Publicado: (2021)