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TLR4 Blockade Using Docosahexaenoic Acid Restores Vulnerability of Drug-Tolerant Tumor Cells and Prevents Breast Cancer Metastasis and Postsurgical Relapse

[Image: see text] Nonmutational mechanisms were recently discovered leading to reversible drug tolerance. Despite the rapid elimination of a majority of tumor cells, a small subpopulation of “‘drug-tolerant”’ cells remain viable with lethal drug exposure, which may further lead to resistance or tumo...

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Detalles Bibliográficos
Autores principales: Wang, Mou, Wang, Yuejing, Liu, Renhe, Yu, Ruilian, Gong, Tao, Zhang, Zhirong, Fu, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125315/
https://www.ncbi.nlm.nih.gov/pubmed/37101603
http://dx.doi.org/10.1021/acsbiomedchemau.2c00061