Efficient Strategy to Design Protease Inhibitors: Application to Enterovirus 71 2A Protease

[Image: see text] One strategy to counter viruses that persistently cause outbreaks is to design molecules that can specifically inhibit an essential multifunctional viral protease. Herein, we present such a strategy using well-established methods to first identify a region present only in viral (bu...

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Detalles Bibliográficos
Autores principales: Chen, Ting, Grauffel, Cédric, Yang, Wei-Zen, Chen, Yi-Ping, Yuan, Hanna S., Lim, Carmay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125330/
https://www.ncbi.nlm.nih.gov/pubmed/37102167
http://dx.doi.org/10.1021/acsbiomedchemau.2c00001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125330/
https://www.ncbi.nlm.nih.gov/pubmed/37102167
http://dx.doi.org/10.1021/acsbiomedchemau.2c00001

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