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Efficient Strategy to Design Protease Inhibitors: Application to Enterovirus 71 2A Protease
[Image: see text] One strategy to counter viruses that persistently cause outbreaks is to design molecules that can specifically inhibit an essential multifunctional viral protease. Herein, we present such a strategy using well-established methods to first identify a region present only in viral (bu...
Autores principales: | Chen, Ting, Grauffel, Cédric, Yang, Wei-Zen, Chen, Yi-Ping, Yuan, Hanna S., Lim, Carmay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125330/ https://www.ncbi.nlm.nih.gov/pubmed/37102167 http://dx.doi.org/10.1021/acsbiomedchemau.2c00001 |
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