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Testing for Phylogenetic Signal in Single-Cell RNA-Seq Data

Phylogenetic methods are emerging as a useful tool to understand cancer evolutionary dynamics, including tumor structure, heterogeneity, and progression. Most currently used approaches utilize either bulk whole genome sequencing or single-cell DNA sequencing and are based on calling copy number alte...

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Detalles Bibliográficos
Autores principales: Moravec, Jiří C., Lanfear, Robert, Spector, David L., Diermeier, Sarah D., Gavryushkin, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125402/
https://www.ncbi.nlm.nih.gov/pubmed/36475926
http://dx.doi.org/10.1089/cmb.2022.0357