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Inhibition of miR-146a Expression and Regulation of Endotoxin Tolerance by Rhesus Theta-Defensin-1

Theta- (θ-) defensins are pleiotropic host defense peptides with antimicrobial- and immune-modulating activities. Immune stimulation of cells with lipopolysaccharide (LPS, endotoxin) activates proinflammatory gene expression and cytokine secretion, both of which are attenuated by rhesus theta-defens...

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Detalles Bibliográficos
Autores principales: Tongaonkar, Prasad, Trinh, Katie K., Ouellette, André J., Selsted, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125762/
https://www.ncbi.nlm.nih.gov/pubmed/37101596
http://dx.doi.org/10.1155/2023/8387330