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Allosteric modulation of GluN1/GluN3 NMDA receptors by GluN1-selective competitive antagonists

NMDA-type ionotropic glutamate receptors are critical for normal brain function and are implicated in central nervous system disorders. Structure and function of NMDA receptors composed of GluN1 and GluN3 subunits are less understood compared to those composed of GluN1 and GluN2 subunits. GluN1/3 re...

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Detalles Bibliográficos
Autores principales: Rouzbeh, Nirvan, Rau, Andrew R., Benton, Avery J., Yi, Feng, Anderson, Carly M., Johns, Mia R., Jensen, Loren, Lotti, James S., Holley, David C., Hansen, Kasper B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125900/
https://www.ncbi.nlm.nih.gov/pubmed/37078900
http://dx.doi.org/10.1085/jgp.202313340