iGEM as a human iPS cell-based global epigenetic modulation detection assay provides throughput characterization of chemicals affecting DNA methylation

Chemical-induced dysregulation of DNA methylation during the fetal period is known to contribute to developmental disorders or increase the risk of certain diseases later in life. In this study, we developed an iGEM (iPS cell-based global epigenetic modulation) detection assay using human induced pl...

Descripción completa

Detalles Bibliográficos
Autores principales: Otsuka, Satoshi, Qin, Xian-Yang, Wang, Wenlong, Ito, Tomohiro, Nansai, Hiroko, Abe, Kuniya, Fujibuchi, Wataru, Nakao, Yoichi, Sone, Hideko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125974/
https://www.ncbi.nlm.nih.gov/pubmed/37095195
http://dx.doi.org/10.1038/s41598-023-33729-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10125974/
https://www.ncbi.nlm.nih.gov/pubmed/37095195
http://dx.doi.org/10.1038/s41598-023-33729-4

Ejemplares similares