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Development of anti-feline PD-1 antibody and its functional analysis

Antibodies against immune checkpoint molecules restore T-cell function by inhibiting the binding of PD-1 and PD-L1 and have been shown to exert therapeutic effects in various human cancers. However, to date, no monoclonal antibody that recognizes feline PD-1 or PD-L1 has been reported, and there are...

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Detalles Bibliográficos
Autores principales: Nishibori, Shoma, Kaneko, Mika K., Nakagawa, Takayuki, Nishigaki, Kazuo, Kato, Yukinari, Igase, Masaya, Mizuno, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126011/
https://www.ncbi.nlm.nih.gov/pubmed/37095139
http://dx.doi.org/10.1038/s41598-023-31543-6