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ALS is imprinted in the chromatin accessibility of blood cells

Amyotrophic Lateral Sclerosis (ALS) is a complex and incurable neurodegenerative disorder in which genetic and epigenetic factors contribute to the pathogenesis of all forms of ALS. The interplay of genetic predisposition and environmental footprints generates epigenetic signatures in the cells of a...

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Detalles Bibliográficos
Autores principales: Kühlwein, Julia K., Ruf, Wolfgang P., Kandler, Katharina, Witzel, Simon, Lang, Christina, Mulaw, Medhanie A., Ekici, Arif B., Weishaupt, Jochen H., Ludolph, Albert C., Grozdanov, Veselin, Danzer, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126052/
https://www.ncbi.nlm.nih.gov/pubmed/37095391
http://dx.doi.org/10.1007/s00018-023-04769-w