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ALS is imprinted in the chromatin accessibility of blood cells
Amyotrophic Lateral Sclerosis (ALS) is a complex and incurable neurodegenerative disorder in which genetic and epigenetic factors contribute to the pathogenesis of all forms of ALS. The interplay of genetic predisposition and environmental footprints generates epigenetic signatures in the cells of a...
Autores principales: | Kühlwein, Julia K., Ruf, Wolfgang P., Kandler, Katharina, Witzel, Simon, Lang, Christina, Mulaw, Medhanie A., Ekici, Arif B., Weishaupt, Jochen H., Ludolph, Albert C., Grozdanov, Veselin, Danzer, Karin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126052/ https://www.ncbi.nlm.nih.gov/pubmed/37095391 http://dx.doi.org/10.1007/s00018-023-04769-w |
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