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Metabolomic differentiation of benign vs malignant pulmonary nodules with high specificity via high-resolution mass spectrometry analysis of patient sera

Differential diagnosis of pulmonary nodules detected by computed tomography (CT) remains a challenge in clinical practice. Here, we characterize the global metabolomes of 480 serum samples including healthy controls, benign pulmonary nodules, and stage I lung adenocarcinoma. The adenocarcinoma demon...

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Detalles Bibliográficos
Autores principales: Yao, Yao, Wang, Xueping, Guan, Jian, Xie, Chuanbo, Zhang, Hui, Yang, Jing, Luo, Yao, Chen, Lili, Zhao, Mingyue, Huo, Bitao, Yu, Tiantian, Lu, Wenhua, Liu, Qiao, Du, Hongli, Liu, Yuying, Huang, Peng, Luan, Tiangang, Liu, Wanli, Hu, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126054/
https://www.ncbi.nlm.nih.gov/pubmed/37095081
http://dx.doi.org/10.1038/s41467-023-37875-1