Cargando…

Metabolomic differentiation of benign vs malignant pulmonary nodules with high specificity via high-resolution mass spectrometry analysis of patient sera

Differential diagnosis of pulmonary nodules detected by computed tomography (CT) remains a challenge in clinical practice. Here, we characterize the global metabolomes of 480 serum samples including healthy controls, benign pulmonary nodules, and stage I lung adenocarcinoma. The adenocarcinoma demon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Yao, Wang, Xueping, Guan, Jian, Xie, Chuanbo, Zhang, Hui, Yang, Jing, Luo, Yao, Chen, Lili, Zhao, Mingyue, Huo, Bitao, Yu, Tiantian, Lu, Wenhua, Liu, Qiao, Du, Hongli, Liu, Yuying, Huang, Peng, Luan, Tiangang, Liu, Wanli, Hu, Yumin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126054/ https://www.ncbi.nlm.nih.gov/pubmed/37095081 http://dx.doi.org/10.1038/s41467-023-37875-1

Ejemplares similares

Utility of peripheral blood macrophage factor Apo10 and TKTL1 as markers in distinguishing malignant from benign lung nodules: a protocol for a prospective cohort study in Southern China
por: Xie, Chuanbo, et al.
Publicado: (2023)

Management of bleeding associated with radiofrequency ablation of benign thyroid nodules
por: Hu, Kunpeng, et al.
Publicado: (2020)

B-mode Ultrasound Characteristics of Thyroid Nodules With High-Benign Probability and Nodules With Risk of Malignancy
por: Sultan, Salahaden R
Publicado: (2023)

Pulmonary Multiple Nodules: Benign or Malignant?
por: Liu, Jing, et al.
Publicado: (2018)

Significance of radiofrequency ablation in large solid benign thyroid nodules
por: Lin, Yan, et al.
Publicado: (2022)

Complications Following Radiofrequency Ablation of Benign Thyroid Nodules: A Systematic Review
por: Wang, Jin-Fen, et al.
Publicado: (2017)

Transcriptomic analysis of humic acid in relieving the inhibitory effect of high nitrogen on soybean nodulation
por: Zhang, Wenhua, et al.
Publicado: (2023)

The efficacy and safety of high-intensity focused ultrasound ablation of benign thyroid nodules
por: Lang, Brian H., et al.
Publicado: (2018)

Comparison of six machine learning methods for differentiating benign and malignant thyroid nodules using ultrasonographic characteristics
por: Liang, Jianguang, et al.
Publicado: (2023)

Benign disease prone to be misdiagnosed as malignant pulmonary nodules: Minute meningothelioid nodules
por: Peng, Xiao‐Xiao, et al.
Publicado: (2019)

Ovarian Cancer Classification based on Mass Spectrometry Analysis of Sera
por: Wu, Baolin, et al.
Publicado: (2007)

Rapid Profiling of Chemical Constituents in Qingfei Paidu Granules Using High Performance Liquid Chromatography Coupled with Q Exactive Mass Spectrometry
por: Fu, Shuai, et al.
Publicado: (2021)

Multiclassifier fusion based on radiomics features for the prediction of benign and malignant primary pulmonary solid nodules
por: Shen, Yao, et al.
Publicado: (2020)

Serum laser Raman spectroscopy as a potential diagnostic tool to discriminate the benignancy or malignancy of pulmonary nodules
por: Luo, Huaichao, et al.
Publicado: (2023)

Metabolic Profiling of Plasma from Benign and Malignant Pulmonary Nodules Patients Using Mass Spectrometry-Based Metabolomics
por: Gao, Liang, et al.
Publicado: (2013)

A Novel Strategy for Single-Session Ultrasound-Guided Radiofrequency Ablation of Large Benign Thyroid Nodules: A Pilot Cohort Study
por: Yao, Zhicheng, et al.
Publicado: (2020)

Natural Course of Benign Thyroid Nodules
por: Kim, Kyung Won
Publicado: (2013)

Efficacy of levothyroxine on benign thyroid nodule
por: Bayani, Mohammadali, et al.
Publicado: (2012)

Identification and Validation of Serum CST1 as a Diagnostic Marker for Differentiating Early-Stage Non-Small Cell Lung Cancer from Pulmonary Benign Nodules
por: Lai, Yanzhen, et al.
Publicado: (2022)

Perithyroidal hemorrhage caused by hydrodissection during radiofrequency ablation for benign thyroid nodules: Two case reports
por: Zheng, Bo-Wen, et al.
Publicado: (2022)

Logistic regression analysis of conventional ultrasonography, strain elastosonography, and contrast-enhanced ultrasound characteristics for the differentiation of benign and malignant thyroid nodules
por: Pang, Tiantian, et al.
Publicado: (2017)

Early assessment of high-intensity focused ultrasound treatment of benign thyroid nodules by scintigraphic means
por: Korkusuz, Huedayi, et al.
Publicado: (2014)

High intensity focused ultrasound (HIFU) ablation of benign thyroid nodules – a systematic review
por: Lang, Brian Hung-Hin, et al.
Publicado: (2017)

Horner’s Syndrome During High-Intensity Focused Ultrasound Ablation for a Benign Thyroid Nodule
por: Ben Hamou, Adrien, et al.
Publicado: (2021)

Feasibility of Using High-Resolution Computed Tomography Features for Invasiveness Differentiation of Malignant Nodules Manifesting as Ground-Glass Nodules
por: Chen, Xinyue, et al.
Publicado: (2022)

Systematic Mining and Evaluation of the Sesquiterpene Skeletons as High Energy Aviation Fuel Molecules
por: Huang, Yanglei, et al.
Publicado: (2023)

Diagnostic accuracy of different computer-aided diagnostic systems for malignant and benign thyroid nodules classification in ultrasound images: A systematic review and meta-analysis protocol
por: Liu, Ruisheng, et al.
Publicado: (2019)

Liquid biopsies to distinguish malignant from benign pulmonary nodules
por: Tao, Rui, et al.
Publicado: (2021)

Assessment of perinodular stiffness in differentiating malignant from benign thyroid nodules
por: Hu, Lei, et al.
Publicado: (2021)

Management of giant benign fibrous histiocytoma in the spinal region with pleural involvement: A case report
por: Liu, Shuzhong, et al.
Publicado: (2019)

Comparison of Natural Course between Thyroid Cancer Nodules and Thyroid Benign Nodules
por: Yun, Kyun-Jin, et al.
Publicado: (2019)

Benign and malignant thyroid nodules with autoimmune thyroiditis
por: Kassi, Georgia N., et al.
Publicado: (2022)

Thyroid nodules with highly suspicious ultrasonographic features, but with benign cytology on two occasions: is malignancy still possible?
por: Rosário, Pedro Weslley, et al.
Publicado: (2016)

Identification of Trace Components in Sauce-Flavor Baijiu by High-Resolution Mass Spectrometry
por: Ge, Jinfeng, et al.
Publicado: (2023)

Thyroid nodules in centenarians: prevalence and relationship to lifestyle characteristics and dietary habits
por: Yao, Yao, et al.
Publicado: (2018)

Identification of benign and malignant thyroid nodules based on dynamic AI ultrasound intelligent auxiliary diagnosis system
por: Wang, Bing, et al.
Publicado: (2022)

Diagnostic value of peripheral blood eosinophils for benign and malignant pulmonary nodule
por: Xiu, Jiawei, et al.
Publicado: (2023)

A new classifier constructed with platelet features for malignant and benign pulmonary nodules based on prospective real-world data
por: Zu, Ruiling, et al.
Publicado: (2022)

Chemical Analysis of the Chinese Liquor Luzhoulaojiao by Comprehensive Two-Dimensional Gas Chromatography/Time-of-Flight Mass Spectrometry
por: Yao, Feng, et al.
Publicado: (2015)

Clinical Analysis of Video-Assisted Thoracoscopic Surgery for Resection of Solitary Pulmonary Nodules and Influencing Factors in the Diagnosis of Benign and Malignant Nodules
por: Yue, Hongxu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1f9b2247tkg1h7ce7lpmik6r6p