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HAPLN1 potentiates peritoneal metastasis in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) frequently metastasizes into the peritoneum, which contributes to poor prognosis. Metastatic spreading is promoted by cancer cell plasticity, yet its regulation by the microenvironment is incompletely understood. Here, we show that the presence of hyaluronan a...

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Detalles Bibliográficos
Autores principales: Wiedmann, Lena, De Angelis Rigotti, Francesca, Vaquero-Siguero, Nuria, Donato, Elisa, Espinet, Elisa, Moll, Iris, Alsina-Sanchis, Elisenda, Bohnenberger, Hanibal, Fernandez-Florido, Elena, Mülfarth, Ronja, Vacca, Margherita, Gerwing, Jennifer, Conradi, Lena-Christin, Ströbel, Philipp, Trumpp, Andreas, Mogler, Carolin, Fischer, Andreas, Rodriguez-Vita, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126109/
https://www.ncbi.nlm.nih.gov/pubmed/37095087
http://dx.doi.org/10.1038/s41467-023-38064-w