Cargando…

A massively parallel screening platform for converting aptamers into molecular switches

Aptamer-based molecular switches that undergo a binding-induced conformational change have proven valuable for a wide range of applications, such as imaging metabolites in cells, targeted drug delivery, and real-time detection of biomolecules. Since conventional aptamer selection methods do not typi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshikawa, Alex M., Rangel, Alexandra E., Zheng, Liwei, Wan, Leighton, Hein, Linus A., Hariri, Amani A., Eisenstein, Michael, Soh, H. Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126150/
https://www.ncbi.nlm.nih.gov/pubmed/37095144
http://dx.doi.org/10.1038/s41467-023-38105-4