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A massively parallel screening platform for converting aptamers into molecular switches
Aptamer-based molecular switches that undergo a binding-induced conformational change have proven valuable for a wide range of applications, such as imaging metabolites in cells, targeted drug delivery, and real-time detection of biomolecules. Since conventional aptamer selection methods do not typi...
Autores principales: | Yoshikawa, Alex M., Rangel, Alexandra E., Zheng, Liwei, Wan, Leighton, Hein, Linus A., Hariri, Amani A., Eisenstein, Michael, Soh, H. Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126150/ https://www.ncbi.nlm.nih.gov/pubmed/37095144 http://dx.doi.org/10.1038/s41467-023-38105-4 |
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