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High concentrations of soluble endoglin can inhibit BMP9 signaling in non-endothelial cells

Endoglin (ENG) is a single-pass transmembrane protein highly expressed on vascular endothelial cells, although low expression levels can be detected in many other cell types. Its extracellular domain can be found in circulation known as soluble endoglin (sENG). Levels of sENG are elevated in many pa...

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Detalles Bibliográficos
Autores principales: Andersson-Rusch, Clara, Liu, Bin, Quist-Løkken, Ingrid, Upton, Paul D., Olsen, Oddrun Elise, Hella, Hanne, Yang, Xudong, Tong, Zhen, Morrell, Nicholas W., Holien, Toril, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126157/
https://www.ncbi.nlm.nih.gov/pubmed/37095146
http://dx.doi.org/10.1038/s41598-023-33352-3