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COVID-19 adenovirus vector vaccine induces higher interferon and pro-inflammatory responses than mRNA vaccines in human PBMCs, macrophages and moDCs

BACKGROUND: During the COVID-19 pandemic multiple vaccines were rapidly developed and widely used throughout the world. At present there is very little information on COVID-19 vaccine interactions with primary human immune cells such as peripheral blood mononuclear cells (PBMCs), monocyte-derived ma...

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Detalles Bibliográficos
Autores principales: Jiang, Miao, Väisänen, Elina, Kolehmainen, Pekka, Huttunen, Moona, Ylä-Herttuala, Seppo, Meri, Seppo, Österlund, Pamela, Julkunen, Ilkka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126225/
https://www.ncbi.nlm.nih.gov/pubmed/37142461
http://dx.doi.org/10.1016/j.vaccine.2023.04.049