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Application of single cell multiomics points to changes in chromatin accessibility near calcitonin receptor like receptor and a possible role for adrenomedullin in the post-shock lung

INTRODUCTION: Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a commonly occurring sequelae of traumatic injury resulting from indirect insults like hypovolemic shock and/or extrapulmonary sepsis. The high lethality rate associated with these pathologies outlines the importance...

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Detalles Bibliográficos
Autores principales: Armstead, Brandon E., Lee, Chung Sunny, Chen, Yaping, Zhao, Runping, Chung, Chun-Shiang, Fredericks, Alger M., Monaghan, Sean F., Ayala, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126233/
https://www.ncbi.nlm.nih.gov/pubmed/37113606
http://dx.doi.org/10.3389/fmed.2023.1003121