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Impact of endogenous glucocorticoid on response to immune checkpoint blockade in patients with advanced cancer

BACKGROUND: Previous studies indicate that exogenous use of glucocorticoid (GC) affects immune checkpoint inhibitor (ICI) efficacy. However, there is a paucity of clinical data evaluating the direct impact of endogenous GC on the efficacy for cancer patients with immune checkpoint blockade. METHODS:...

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Detalles Bibliográficos
Autores principales: Cui, Yu, Han, Xinyue, Liu, Hongtao, Xie, Qi, Guan, Yaping, Yin, Beibei, Xiao, Junjuan, Feng, Dongfeng, Wang, Xuan, Li, Junwei, Chen, Jinghua, Liu, Xiaolin, Li, Xingyu, Nie, Weiwei, Ma, Lin, Liu, Hairong, Liang, Jing, Li, Yan, Wang, Baocheng, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126286/
https://www.ncbi.nlm.nih.gov/pubmed/37114049
http://dx.doi.org/10.3389/fimmu.2023.1081790