DNA immunization with in silico predicted T-cell epitopes protects against lethal SARS-CoV-2 infection in K18-hACE2 mice

The global SARS-CoV-2 pandemic caused significant social and economic disruption worldwide, despite highly effective vaccines being developed at an unprecedented speed. Because the first licensed vaccines target only single B-cell antigens, antigenic drift could lead to loss of efficacy against emer...

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Detalles Bibliográficos
Autores principales: Persson, Gry, Restori, Katherine H., Emdrup, Julie Hincheli, Schussek, Sophie, Klausen, Michael Schantz, Nicol, McKayla J., Katkere, Bhuvana, Rønø, Birgitte, Kirimanjeswara, Girish, Sørensen, Anders Bundgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126292/
https://www.ncbi.nlm.nih.gov/pubmed/37114047
http://dx.doi.org/10.3389/fimmu.2023.1166546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126292/
https://www.ncbi.nlm.nih.gov/pubmed/37114047
http://dx.doi.org/10.3389/fimmu.2023.1166546

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