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DNA immunization with in silico predicted T-cell epitopes protects against lethal SARS-CoV-2 infection in K18-hACE2 mice
The global SARS-CoV-2 pandemic caused significant social and economic disruption worldwide, despite highly effective vaccines being developed at an unprecedented speed. Because the first licensed vaccines target only single B-cell antigens, antigenic drift could lead to loss of efficacy against emer...
Autores principales: | Persson, Gry, Restori, Katherine H., Emdrup, Julie Hincheli, Schussek, Sophie, Klausen, Michael Schantz, Nicol, McKayla J., Katkere, Bhuvana, Rønø, Birgitte, Kirimanjeswara, Girish, Sørensen, Anders Bundgaard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126292/ https://www.ncbi.nlm.nih.gov/pubmed/37114047 http://dx.doi.org/10.3389/fimmu.2023.1166546 |
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