Characterization of the functional and transcriptomic effects of pro-inflammatory cytokines on human EndoC-βH5 beta cells

OBJECTIVE: EndoC-βH5 is a newly established human beta-cell model which may be superior to previous model systems. Exposure of beta cells to pro-inflammatory cytokines is widely used when studying immune-mediated beta-cell failure in type 1 diabetes. We therefore performed an in-depth characterizati...

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Detalles Bibliográficos
Autores principales: Frørup, Caroline, Gerwig, Rebekka, Svane, Cecilie Amalie Søndergaard, Mendes Lopes de Melo, Joana, Henriksen, Kristine, Fløyel, Tina, Pociot, Flemming, Kaur, Simranjeet, Størling, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126300/
https://www.ncbi.nlm.nih.gov/pubmed/37113489
http://dx.doi.org/10.3389/fendo.2023.1128523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126300/
https://www.ncbi.nlm.nih.gov/pubmed/37113489
http://dx.doi.org/10.3389/fendo.2023.1128523

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