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Characterization of pain-, anxiety-, and cognition-related behaviors in the complete Freund's adjuvant model of chronic inflammatory pain in Wistar–Kyoto rats

INTRODUCTION: Chronic pain is often associated with comorbid anxiety and cognitive dysfunction, negatively affecting therapeutic outcomes. The influence of genetic background on such interactions is poorly understood. The stress-hyperresponsive Wistar–Kyoto (WKY) rat strain, which models aspects of...

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Detalles Bibliográficos
Autores principales: Ferdousi, Mehnaz I., Calcagno, Patricia, Sanchez, Connie, Smith, Karen L., Kelly, John P., Roche, Michelle, Finn, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126329/
https://www.ncbi.nlm.nih.gov/pubmed/37113211
http://dx.doi.org/10.3389/fpain.2023.1131069