Case report: anaplastic lymphoma kinase (ALK) rearranged adenocarcinoma with high level of microsatellite instability response to pembrolizumab

The presence of anaplastic lymphoma kinase (ALK) rearrangement is reported to be related to the lack of efficacy of immune checkpoint inhibitors (ICIs). High levels of microsatellite instability (MSI-high) are important biomarkers of ICIs, particularly in colorectal cancer. The therapeutic effect of...

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Detalles Bibliográficos
Autores principales: Shigeta, Naoko, Murakami, Shuji, Yokose, Tomoyuki, Miyagi, Yohei, Saito, Haruhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126330/
https://www.ncbi.nlm.nih.gov/pubmed/37114121
http://dx.doi.org/10.3389/fonc.2023.1110638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126330/
https://www.ncbi.nlm.nih.gov/pubmed/37114121
http://dx.doi.org/10.3389/fonc.2023.1110638

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