Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis

Candida parapsilosis is an emerging major human fungal pathogen. Echinocandins are first-line antifungal drugs for the treatment of invasive Candida infections. In clinical isolates, tolerance to echinocandins in Candida species is mostly due to point mutations of FKS genes, which encode the target...

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Detalles Bibliográficos
Autores principales: Sun, Liu-liu, Li, Hao, Yan, Tian-hua, Cao, Yong-bing, Jiang, Yuan-ying, Yang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126355/
https://www.ncbi.nlm.nih.gov/pubmed/37113223
http://dx.doi.org/10.3389/fmicb.2023.1137083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126355/
https://www.ncbi.nlm.nih.gov/pubmed/37113223
http://dx.doi.org/10.3389/fmicb.2023.1137083

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