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Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data

Machine learning (ML) algorithms are powerful tools that are increasingly being used for sepsis biomarker discovery in RNA-Seq data. RNA-Seq datasets contain multiple sources and types of noise (operator, technical and non-systematic) that may bias ML classification. Normalisation and independent ge...

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Detalles Bibliográficos
Autores principales: Parkinson, Edward, Liberatore , Federico, Watkins , W. John, Andrews , Robert, Edkins , Sarah, Hibbert , Julie, Strunk , Tobias, Currie , Andrew, Ghazal , Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126415/
https://www.ncbi.nlm.nih.gov/pubmed/37113992
http://dx.doi.org/10.3389/fgene.2023.1158352