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Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine

Influenza virus poses an ongoing human health threat with pandemic potential. Due to mutations in circulating strains, formulating effective vaccines remains a challenge. The use of computationally optimized broadly reactive antigen (COBRA) hemagglutinin (HA) proteins is a promising vaccine strategy...

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Detalles Bibliográficos
Autores principales: Dzimianski, John V., Han, Julianna, Sautto, Giuseppe A., O’Rourke, Sara M., Cruz, Joseph M., Pierce, Spencer R., Ecker, Jeffrey W., Carlock, Michael A., Nagashima, Kaito A., Mousa, Jarrod J., Ross, Ted M., Ward, Andrew B., DuBois, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126545/
https://www.ncbi.nlm.nih.gov/pubmed/37185989
http://dx.doi.org/10.1038/s42003-023-04793-3