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Biphasic Dose-Response of Mn-Induced Mitochondrial Damage, PINK1/Parkin Expression, and Mitophagy in SK-N-SH Cells

Excessive manganese (Mn) exposure produces neurotoxicity with mitochondrial damage. Mitophagy is a protective mechanism to eliminate damaged mitochondria to protect cells. The aim of this study was to determine the dose-response of Mn-induced mitochondria damage, the expression of mitophagy-mediated...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Hu, Hong-Tao, Cao, Yu-Min, Jiang, Zhi-Gang, Liu, Jie, Fan, Qi-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126627/
https://www.ncbi.nlm.nih.gov/pubmed/37113652
http://dx.doi.org/10.1177/15593258231169392