Cargando…

Biphasic Dose-Response of Mn-Induced Mitochondrial Damage, PINK1/Parkin Expression, and Mitophagy in SK-N-SH Cells

Excessive manganese (Mn) exposure produces neurotoxicity with mitochondrial damage. Mitophagy is a protective mechanism to eliminate damaged mitochondria to protect cells. The aim of this study was to determine the dose-response of Mn-induced mitochondria damage, the expression of mitophagy-mediated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yue, Hu, Hong-Tao, Cao, Yu-Min, Jiang, Zhi-Gang, Liu, Jie, Fan, Qi-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126627/ https://www.ncbi.nlm.nih.gov/pubmed/37113652 http://dx.doi.org/10.1177/15593258231169392

Ejemplares similares

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
por: Matsuda, Noriyuki, et al.
Publicado: (2010)

PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
por: Kubli, Dieter A., et al.
Publicado: (2015)

Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin‐mediated mitophagy
por: Ivankovic, Davor, et al.
Publicado: (2015)

Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles
por: Ramirez, Adrian, et al.
Publicado: (2022)

Mitophagy and Parkinson's disease: The PINK1–parkin link()
por: Deas, Emma, et al.
Publicado: (2011)

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
por: Shiba-Fukushima, Kahori, et al.
Publicado: (2012)

Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria
por: Xiao, Bin, et al.
Publicado: (2017)

Loss of iron triggers PINK1/Parkin-independent mitophagy
por: Allen, George F G, et al.
Publicado: (2013)

Correction: Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria
por: Xiao, Bin, et al.
Publicado: (2018)

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
por: Ashrafi, Ghazaleh, et al.
Publicado: (2014)

Mitochondrial Ca(2+) oscillation induces mitophagy initiation through the PINK1-Parkin pathway
por: Yu, Zhengying, et al.
Publicado: (2021)

The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications
por: Durcan, Thomas M., et al.
Publicado: (2015)

Deficiency of parkin and PINK1 impairs age-dependent mitophagy in Drosophila
por: Cornelissen, Tom, et al.
Publicado: (2018)

PINK1-parkin-mediated neuronal mitophagy deficiency in prion disease
por: Li, Jie, et al.
Publicado: (2022)

Inhibition of mitoNEET induces Pink1-Parkin-mediated mitophagy
por: Lee, Seunghee, et al.
Publicado: (2022)

Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson’s disease
por: Koentjoro, Brianada, et al.
Publicado: (2017)

PINK1/Parkin-mediated mitophagy inhibits warangalone-induced mitochondrial apoptosis in breast cancer cells
por: Mao, Lianzhi, et al.
Publicado: (2021)

Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
por: Lee, Juliette J., et al.
Publicado: (2018)

Salidroside Protects Dopaminergic Neurons by Enhancing PINK1/Parkin-Mediated Mitophagy
por: Li, Ruru, et al.
Publicado: (2019)

PINK1/Parkin-mediated mitophagy in mechanical ventilation-induced diaphragmatic dysfunction
por: Yong, Hui, et al.
Publicado: (2021)

Erythropoietin Mitigates Diabetic Nephropathy by Restoring PINK1/Parkin-Mediated Mitophagy
por: Yi, Xinyao, et al.
Publicado: (2022)

DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy
por: Imberechts, Dorien, et al.
Publicado: (2022)

NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy
por: Kataura, Tetsushi, et al.
Publicado: (2022)

PINK1-Parkin-Mediated Mitophagy Protects Mitochondrial Integrity and Prevents Metabolic Stress-Induced Endothelial Injury
por: Wu, Weiwei, et al.
Publicado: (2015)

Commentary: Nix restores mitophagy and mitochondrial function to protect against PINK1/Parkin-related Parkinson's disease
por: Park, Jin-Sung, et al.
Publicado: (2017)

Berberine Promotes Cardiac Function by Upregulating PINK1/Parkin-Mediated Mitophagy in Heart Failure
por: Abudureyimu, Miyesaier, et al.
Publicado: (2020)

Dendrobium nobile Lindl. alkaloids alleviate Mn-induced neurotoxicity via PINK1/Parkin-mediated mitophagy in PC12 cells
por: Fu, Xiaolong, et al.
Publicado: (2021)

Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?
por: Grenier, Karl, et al.
Publicado: (2013)

Morphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink–parkin pathway
por: Amadoro, Giuseppina, et al.
Publicado: (2014)

Regulatory Roles of PINK1-Parkin and AMPK in Ubiquitin-Dependent Skeletal Muscle Mitophagy
por: Seabright, Alex P., et al.
Publicado: (2020)

The PINK1—Parkin mitophagy signalling pathway is not functional in peripheral blood mononuclear cells
por: Bradshaw, Aaron V., et al.
Publicado: (2021)

PINK1/Parkin‐mediated mitophagy enhances the survival of Staphylococcus aureus in bovine macrophages
por: Zhou, Xi, et al.
Publicado: (2023)

A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit
por: Waters, Christopher S., et al.
Publicado: (2023)

Mitochondrial targeted HSP90 inhibitor Gamitrinib-TPP (G-TPP) induces PINK1/Parkin-dependent mitophagy
por: Fiesel, Fabienne C., et al.
Publicado: (2017)

δ-opioid receptor activation protects against Parkinson’s disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy
por: Xu, Yuan, et al.
Publicado: (2020)

Mitochondrial quality control beyond PINK1/Parkin
por: von Stockum, Sophia, et al.
Publicado: (2018)

Counteracting PINK/Parkin Deficiency in the Activation of Mitophagy: A Potential Therapeutic Intervention for Parkinson’s Disease
por: Nardin, Alice, et al.
Publicado: (2016)

ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts
por: Qi, Yongmei, et al.
Publicado: (2016)

Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells
por: Tan, Jin, et al.
Publicado: (2018)

PINK1/Parkin-mediated mitophagy is activated in cisplatin nephrotoxicity to protect against kidney injury
por: Wang, Ying, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_80jusgs6apoudn8v2vv77ksecm