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The influence of immortal time bias in observational studies examining associations of antifibrotic therapy with survival in idiopathic pulmonary fibrosis: A simulation study

BACKGROUND: Immortal time bias (ITB) has been overlooked in idiopathic pulmonary fibrosis (IPF). We aimed to identify the presence of ITB in observational studies examining associations between antifibrotic therapy and survival in patients with IPF and illustrate how ITB may affect effect size estim...

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Detalles Bibliográficos
Autores principales: Zheng, Qiang, Otahal, Petr, Cox, Ingrid A., de Graaff, Barbara, Campbell, Julie A., Ahmad, Hasnat, Walters, E. Haydn, Palmer, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126672/
https://www.ncbi.nlm.nih.gov/pubmed/37113607
http://dx.doi.org/10.3389/fmed.2023.1157706