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The influence of immortal time bias in observational studies examining associations of antifibrotic therapy with survival in idiopathic pulmonary fibrosis: A simulation study
BACKGROUND: Immortal time bias (ITB) has been overlooked in idiopathic pulmonary fibrosis (IPF). We aimed to identify the presence of ITB in observational studies examining associations between antifibrotic therapy and survival in patients with IPF and illustrate how ITB may affect effect size estim...
Autores principales: | Zheng, Qiang, Otahal, Petr, Cox, Ingrid A., de Graaff, Barbara, Campbell, Julie A., Ahmad, Hasnat, Walters, E. Haydn, Palmer, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126672/ https://www.ncbi.nlm.nih.gov/pubmed/37113607 http://dx.doi.org/10.3389/fmed.2023.1157706 |
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