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APOL1 and APOL1-Associated Kidney Disease: A Common Disease, an Unusual Disease Gene − Proceedings of the Henry Shavelle Professorship

BACKGROUND: Genetic variants in APOL1 are a major contributor to the increased risk of kidney disease in people of recent African ancestry. SUMMARY: Two alleles in the APOL1 gene, referred to as G1 and G2, confer increased risk of kidney disease under a recessive model of risk inheritance. Disease r...

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Detalles Bibliográficos
Autores principales: Pollak, Martin R., Friedman, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126737/
https://www.ncbi.nlm.nih.gov/pubmed/37113494
http://dx.doi.org/10.1159/000529227