Gain‑of‑function of IDO in DCs inhibits T cell immunity by metabolically regulating surface molecules and cytokines

Both tolerogenicity and immunogenicity of dendritic cells (DCs) are regulated by their intracellular metabolism. As a rate-limiting enzyme of tryptophan (Trp) metabolism, indoleamine 2,3-dioxygenase (IDO) is involved in regulating the functions of numerous cell types, including DCs, a subset of whic...

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Detalles Bibliográficos
Autores principales: Wang, Fengge, Liu, Lei, Wang, Juncheng, Liu, Meng, Zhang, Wenjie, Zhao, Lin, Zhai, Chengfeng, Xu, Yuekang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126813/
https://www.ncbi.nlm.nih.gov/pubmed/37114180
http://dx.doi.org/10.3892/etm.2023.11933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126813/
https://www.ncbi.nlm.nih.gov/pubmed/37114180
http://dx.doi.org/10.3892/etm.2023.11933

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