Modelling the erythroblastic island niche of dyserythropoietic anaemia type IV patients using induced pluripotent stem cells

Introduction: Congenital dyserythropoietic anaemia (CDA) type IV has been associated with an amino acid substitution, Glu325Lys (E325K), in the transcription factor KLF1. These patients present with a range of symptoms, including the persistence of nucleated red blood cells (RBCs) in the peripheral...

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Detalles Bibliográficos
Autores principales: May, Alisha, Ventura, Telma, Fidanza, Antonella, Volmer, Helena, Taylor, Helen, Romanò, Nicola, D’Souza, Sunita L., Bieker, James J., Forrester, Lesley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126837/
https://www.ncbi.nlm.nih.gov/pubmed/37113767
http://dx.doi.org/10.3389/fcell.2023.1148013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126837/
https://www.ncbi.nlm.nih.gov/pubmed/37113767
http://dx.doi.org/10.3389/fcell.2023.1148013

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