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Modelling the erythroblastic island niche of dyserythropoietic anaemia type IV patients using induced pluripotent stem cells
Introduction: Congenital dyserythropoietic anaemia (CDA) type IV has been associated with an amino acid substitution, Glu325Lys (E325K), in the transcription factor KLF1. These patients present with a range of symptoms, including the persistence of nucleated red blood cells (RBCs) in the peripheral...
Autores principales: | May, Alisha, Ventura, Telma, Fidanza, Antonella, Volmer, Helena, Taylor, Helen, Romanò, Nicola, D’Souza, Sunita L., Bieker, James J., Forrester, Lesley M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126837/ https://www.ncbi.nlm.nih.gov/pubmed/37113767 http://dx.doi.org/10.3389/fcell.2023.1148013 |
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